M. J. Haughey

First passage time analysis of spatial mutation patterns reveals evolutionary dynamics of pre-existing resistance in colorectal cancer

This paper introduces a first passage time analysis framework to quantify spatial mutation patterns in colorectal cancer, revealing sub-clonal dynamics and replicative advantages of mutant cells.

Clonal dynamics of normal hepatocyte expansions in homeostatic human livers and their association with the biliary epithelium

The paper studies clonal hepatocyte expansions in normal human livers, finding a periportal progenitor niche and slow clonal expansion dynamics.