Author

M. J. Oudin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2

Frequent Co-Authors

J. R. Guarin· 3 shared S. L. Payne· 3 shared T. T. Le· 3 shared H. Borges· 2 shared J. P. Fatherree· 2 shared M. Levin· 2 shared R. A. McGinn· 2 shared S. J. Conner· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

J. R. Guarin

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Author profile →

7 papers

Recent·Most cited

Age and obesity-driven changes in the extracellular matrix of the primary tumor and metastatic site influence tumor invasion and metastatic outgrowth

S. J. Conner, J. R. Guarin, H. Borges, K. J. Salhany, D. N. Mensah, G. A. Hamilton, G. H. Le, M. J. Oudin

This study shows that age and obesity alter the extracellular matrix (ECM) in primary tumors and metastatic sites, promoting tumor invasion and metastasis in triple-negative breast cancer.

bioRxiv · Aug 24, 2023 · PreprintCancer Biology

Cell morphology best predicts tumorigenicity and metastasis in vivo across multiple TNBC cell lines of different metastatic potential

S. J. Conner, J. R. Guarin, T. T. Le, J. P. Fatherree, C. A. Kelley, S. L. Payne, K. Salhany, R. A. McGinn, E. Henrich, A. Yui, S. R. Parker, D. Srinivasan, H. Bloomer, H. Borges, M. J. Oudin

This study identifies cell morphology as the best predictor of metastatic potential in TNBC cell lines using in vivo and in vitro assays.

bioRxiv · Jun 14, 2023 · PreprintCancer Biology

Potassium channel-driven bioelectric signaling regulates metastasis in triple-negative breast cancer

S. L. Payne, P. Ram, D. H. Srinivasan, T. T. Le, M. Levin, M. J. Oudin

This study shows that altering potassium channel expression changes resting membrane potential in TNBC cells, increasing invasion and metastasis through cadherin-11 and MAPK pathway changes, and suggests repurposing potassium channel blockers as a therapeutic strategy.

bioRxiv · Apr 6, 2021Cancer Biology

Chemotherapy-induced collagen IV drives cancer cell invasion through activation of Src/FAK signaling

J. P. Fatherree, J. R. Guarin, R. A. McGinn, S. P. Naber, M. J. Oudin

This study shows chemotherapy alters the extracellular matrix of breast tumors, increasing invasion of residual cancer cells through collagen IV and Src/FAK signaling.

bioRxiv · Apr 1, 2021 · PreprintCancer Biology

RNA-sequencing indicates immune cell signaling and inflammatory gene expression in cardiac fibroblasts increases with developmental age

L. R. Perreault, T. T. Le, M. J. Oudin, L. D. Black

This study uses RNA-seq to analyze cardiac fibroblasts from fetal, neonatal, and adult rats, finding increased immune signaling and inflammatory gene expression with age.

bioRxiv · Mar 1, 2021 · PreprintCell Biology

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

A. Wishart, Y. Peng, S. Conner, J. Guarin, R. Crews, J. Fatherree, A. S. Greenberg, M. J. Oudin

This study shows obesity alters ECM composition in mammary tissue, promoting breast cancer invasion and metastasis through Collagen VI and EGFR signaling.

bioRxiv · Jan 29, 2020 · PreprintCancer Biology

Defined extracellular ionic solutions to study and manipulate the cellular resting membrane potential

M. Bonzanni, S. L. Payne, M. Adelfio, D. Kaplan, M. Levin, M. J. Oudin

The paper introduces a method to manipulate and study the resting membrane potential in non-excitable cells using defined extracellular ionic solutions and voltage-sensitive dyes.

bioRxiv · Sep 27, 2019Cell Biology