Author

M. J. van Belkum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Fischer· 2 shared D. L. Tyrrell· 2 shared E. Arutyunova· 2 shared H. S. Young· 2 shared J. C. Vederas· 2 shared M. B. Khan· 2 shared M. J. Lemieux· 2 shared R. T. McKay· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

C. Fischer

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2 papers

Recent·Most cited

BiophysicsbioRxivFeb 16, 2021

N-Terminal finger stabilizes the reversible feline drug GC376 in SARS-CoV-2 Mpro

E. Arutyunova, M. B. Khan, C. Fischer…·M. J. Lemieux

This study characterizes the reversible inhibition of SARS-CoV-2 and SARS-CoV Mpro by GC376, showing nanomolar Ki values and domain swapping in the drug-bound structures.

DOI 10.1016/j.jmb.2021.167003

structural biologyexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivMay 3, 2020

Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

W. Vuong, M. B. Khan, C. Fischer…·M. J. Lemieux

This paper shows that feline coronavirus drugs inhibit SARS-CoV-2 main protease and block virus replication in cell culture with low toxicity.

DOI 10.1038/s41467-020-18096-2

proteomicsexperimental assay

𝕏 PostBluesky