Author

M. K. Dame

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. R. Spence· 3 shared D. Attili· 2 shared J. Varani· 2 shared K. Karpoff· 2 shared M. S. Bohm· 2 shared S. D. McClintock· 2 shared Y.-H. Tsai· 2 shared A. Bosio· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

J. R. Spence

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Author profile →

3 papers

Recent·Most cited

In vitro models of the human esophagus reveal ancestrally diverse response to injury

D. Ferrer-Torres, J. H. Wu, C. J. Zhang, M. A. Hammer, M. K. Dame, A. Wu, E. M. Holloway, K. Karpoff, C. L. McCarthy, M. S. Bohm, S. Huang, Y.-H. Tsai, S. P. Hogan, D. K. Turgeon, J. Lin, , J. R. Spence

The paper develops an in vitro model of the human esophagus to study ancestral differences in response to bile acid injury, finding significant differences between European American and African American-derived cells.

bioRxiv · May 20, 2021 · PreprintCell Biology

Differentiation of Human Colon Tissue In Culture: Effects of calcium on trans-epithelial electrical resistance and tissue cohesive properties

S. D. McClintock, M. K. Dame, A. Richter, D. Attili, S. S. Silvestri, M. M. Berner, M. S. Bohm, K. Karpoff, C. McCarthy, J. R. Spence, J. Varani, M. N. Aslam

This study examines how calcium levels affect colonoid tissue barrier function and cohesion, finding that low calcium supports permeability barriers while higher levels enhance tissue cohesion.

bioRxiv · Aug 22, 2019Physiology

Identification, Isolation, and Characterization of Human LGR5-positive Colon Adenoma Cells

M. K. Dame, D. Attili, S. D. McClintock, P. H. Dedhia, P. Ouilette, O. Hardt, A. M. Chin, X. Xue, J. Laliberte, E. L. Katz, G. M. Newsome, D. Hill, A. Miller, Y.-H. Tsai, D. Agorku, , J. A. Colacino

The paper isolates and characterizes LGR5-positive cells from human colon adenomas using organoids and RNA-sequencing, identifying correlations with CRC-specific genes.

Development · Mar 14, 2018Peer-reviewedCancer Biology