A Human Liver Organoid Screening Platform for DILI Risk Prediction
C. J. Zhang, S. R. Meyer, M. J. O'Meara, S. Huang, M. M. Capeling, D. Ferrer-Torres, C. J. Childs, J. R. Spence, R. J. Fontana, J. Z. Sexton
This study evaluates human liver organoids for DILI risk prediction using high-throughput screening and a liver-on-chip system, showing enhanced predictive capacity and physiological relevance.
bioRxiv · Aug 26, 2021Pharmacology & Toxicology