M. Kalamvoki

The Role of the Tyrosine-Based Sorting Signals of the ORF3a Protein of SARS-CoV-2 on Intracellular Trafficking, Autophagy, and Apoptosis

This study investigates how tyrosine-based sorting signals in the ORF3a protein of SARS-CoV-2 affect intracellular trafficking, apoptosis, and autophagy, finding that multiple motifs are required for efficient transport and that surface expression is not necessary for autophagy.

SARS-CoV-2 harnesses host translational shutoff and autophagy to optimize virus yields: The role of the envelope (E) protein

This paper investigates how SARS-CoV-2 uses the envelope (E) protein to manipulate host translational shutoff and autophagy to enhance virus production.

The Envelope Protein of SARS-CoV-2 Inhibits Viral Protein Synthesis and Infectivity of Human Immunodeficiency Virus type 1 (HIV-1)

This study shows that SARS-CoV-2 and SARS-CoV E proteins significantly reduce HIV-1 infectivity and protein synthesis by inducing ER stress and eIF-2 phosphorylation, while other coronavirus E proteins have a lesser effect.