MicrobiologybioRxivPreprint
The Envelope Protein of SARS-CoV-2 Inhibits Viral Protein Synthesis and Infectivity of Human Immunodeficiency Virus type 1 (HIV-1)
E. B. Stephens, W. Henke, S. Polpitiya Arachchige…·M. Kalamvoki
This study shows that SARS-CoV-2 and SARS-CoV E proteins significantly reduce HIV-1 infectivity and protein synthesis by inducing ER stress and eIF-2 phosphorylation, while other coronavirus E proteins have a lesser effect.
DOI 10.1101/2022.03.23.485576