Author

M. L. Miller

Primary ORCID profile (0000-0002-6350-5706 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

M. L. MilleriD1 paper · Columbia University

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

A. C. Machel· 1 shared A. Chow· 1 shared A. J. Minn· 1 shared A. J. Plodkowski· 1 shared A. J. Schoenfeld· 1 shared A. Jimenez-Sanchez· 1 shared A. Snyder· 1 shared A. Vargas· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. C. Machel

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3 papers

Recent·Most cited

Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer

D. Memon, H. Rizvi, G. Fromm, J. Lihm, A. J. Schoenfeld, J. L. Sauter, J. Luo, A. Chow, U. K. Bhanot, C. McCarthy, D. Ye, C. M. Vanderbilt, C. Liu, M. Abu-Akeel, A. J. Plodkowski, , M. D. Hellmann

This study characterizes clinical and molecular features of acquired resistance to PD-(L)1 blockade in NSCLC, identifying persistent inflammation and dysfunctional IFN signaling as key features.

bioRxiv · Jul 21, 2021Cancer Biology

Resolving Tumour Clonal Heterogeneity and Spatial Complexity using Nuclear Tandem Epitope Protein (nTEP) Barcoding

M. B. Gill, S. Koplev, A. C. Machel, M. L. Miller

This paper introduces nTEP barcoding to spatially resolve tumour clones and their interactions with the microenvironment using multiplexed antibody imaging.

bioRxiv · Oct 30, 2018 · PreprintCancer Biology

Unraveling Tumor-Immune Heterogeneity in Advanced Ovarian Cancer Uncovers Immunogenic Effect of Chemotherapy

A. Jimenez-Sanchez, P. Cybulska, K. Lavigne, T. Walther, I. Nikolovski, Y. Mazaheri, B. Weigelt, D. S. Chi, K. J. Park, T. Hollmann, D.-L. Couturier, A. Vargas, J. D. Brenton, E. Sala, A. Snyder, M. L. Miller

This study analyzes tumor-immune heterogeneity in ovarian cancer before and after chemotherapy, finding that chemotherapy increases cytotoxic immune activation in site-matched samples.

bioRxiv · Oct 17, 2018Cancer Biology