M. Le Gall

T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including Hepatocyte Growth factor

This study identifies an inflammatory microenvironment in T-ALL that supports progression, with HGF as a potential therapeutic target.

Development of rat organoids to study intestinal adaptations after Roux-en-Y Gastric Bypass

This study develops a protocol for growing rat small intestine organoids and finds no significant differences in organoid size or gene expression between RYGB and Sham-operated rats.

RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

The paper shows RNA G-quadruplexes regulate mitochondrial function by modulating cytoplasmic mRNA translation of nuclear-encoded mitochondrial proteins, impacting energy metabolism and cancer cell proliferation.

Loss of intestinal ChREBP impairs absorption of dietary sugars and prevents glycemic excursion curves

This study shows that loss of intestinal ChREBP reduces glucose absorption and delays glycemic responses by impairing sugar transporters and enzymes.

Monolayer graphene-on-polymer dressings promote healing and stabilize skin temperature on acute and chronic wound models.

This study evaluates graphene-on-polymer dressings for wound healing, showing accelerated healing and temperature stabilization in acute and chronic wound models.

The Autophagy Receptor TAX1BP1 (T6BP) is a novel player in antigen presentation by MHC-II molecules.

This study identifies T6BP as a critical regulator of endogenous MHC-II antigen presentation by affecting peptide loading and CD74 stability.

USP9X deubiquitinase couples the pluripotency network and cell metabolism to regulate ESC differentiation potential

This study identifies USP9X as a regulator of ESC differentiation potential by linking pluripotency networks and metabolism.