Author

R. Jeger-Madiot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

I. Staropoli· 2 shared J. Kervevan· 2 shared L. A. Chakrabarti· 2 shared O. Schwartz· 2 shared R. Robinot· 2 shared S. Gellenoncourt· 2 shared A. Esclatine· 1 shared A. Kumari· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

I. Staropoli

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Recapitulating memory B cell responses in a Lymphoid Organ-Chip to evaluate mRNA vaccine boosting strategies

R. Jeger-Madiot, D. Planas, I. Staropoli, J. Kervevan, H. Mary, C. Collina, B. F. Fonseca, H. Debarnot, R. Robinot, S. Gellenoncourt, O. Schwartz, L. Ewart, M. Bscheider, S. Gobaa, L. A. Chakrabarti

The paper develops a Lymphoid Organ-Chip to evaluate mRNA vaccine boosting strategies by mimicking immune responses to SARS-CoV-2 Spike protein and comparing monovalent and bivalent vaccines.

bioRxiv · Feb 2, 2024 · PreprintImmunology

The spike-stabilizing D614G mutation interacts with S1/S2 cleavage site mutations to promote the infectious potential of SARS-CoV-2 variants

S. Gellenoncourt, N. Saunders, R. Robinot, L. Auguste, M. M. Rajah, J. Kervevan, R. Jeger-Madiot, I. Staropoli, C. Planchais, H. Mouquet, J. Buchrieser, O. Schwartz, L. A. Chakrabarti

This study shows the D614G mutation enhances the infectious potential of SARS-CoV-2 variants by synergizing with cleavage site mutations like P681H/R to increase spike fusogenicity.

bioRxiv · May 20, 2022Microbiology

The Autophagy Receptor TAX1BP1 (T6BP) is a novel player in antigen presentation by MHC-II molecules.

M. Pereira, C. Richetta, G. Sarango, A. Kumari, M. Ghosh, L. Bertrand, C. Pionneau, M. Le Gall, S. Gregoire, R. Jeger-Madiot, E. Rosoy, F. Subra, O. Delelis, M. Faure, A. Esclatine, , A. Moris

This study identifies T6BP as a critical regulator of endogenous MHC-II antigen presentation by affecting peptide loading and CD74 stability.

bioRxiv · Apr 21, 2021 · PreprintImmunology