Author

M. M. Fernandez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:transcription & RNA processing· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

E. L. Malchiodi· 2 shared G. Ghosh· 2 shared K. Saha· 2 shared T. Biswas· 2 shared A. Buschiazzo· 1 shared C. E. Argarana· 1 shared D. Meek· 1 shared E. Tanner· 1 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

E. L. Malchiodi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code

K. Saha, M. M. Fernandez, T. Biswas, S. Joseph, G. Ghosh

The paper investigates how a three-dimensional pre-mRNA structural scaffold influences spliceosomal component recruitment beyond traditional splice signals.

Nucleic Acids Research · Jun 23, 2021Peer-reviewedBiochemistry

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel, inducing DNA-dissociation via a transmission spine

J. Lara, L. Diacovich, F. Trajtenberg, N. Larrieux, E. L. Malchiodi, M. M. Fernandez, G. Gago, H. Gramajo, A. Buschiazzo

This study reveals how M. tuberculosis FasR senses long fatty acyl-CoA through a tunnel, inducing DNA dissociation via a transmission spine.

Nature Communications · Jul 24, 2020Peer-reviewedMicrobiology

A novel DNA binding mode, conformational change and intramolecular signaling in MutS upon mismatch recognition in replication DNA structures

M. I. Ibanez, L. M. Margara, S. D. Castell, M. M. Fernandez, E. L. Malchiodi, G. G. Montich, V. Miguel, C. E. Argarana, M. R. Monti

This study identifies a novel DNA binding mode and conformational change in MutS when recognizing mismatches in primed DNA replication structures.

bioRxiv · May 1, 2020 · PreprintBiochemistry

Structural disruption of exonic stem-loops immediately upstream of the intron regulates mammalian splicing

K. Saha, W. England, M. M. Fernandez, T. Biswas, R. Spitale, G. Ghosh

The paper shows that exonic stem-loops upstream of introns regulate splicing by modulating splicing factor accessibility.

bioRxiv · Apr 21, 2020Biochemistry

Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering

W. Orapiriyakul, M. Tsimbouri, P. Childs, P. Campsie, J. Wells, M. M. Fernandez, K. Burgess, E. Tanner, M. Tassieri, D. Meek, M. Vassalli, M. Biggs, M. Salmeron-Sanchez, R. Oreffo, S. Reid, M. Dalby

This study shows that nanovibrational stimulation of MSCs induces ROS and low-level inflammation, mimicking natural bone healing, and uses this to design a 3D bone tissue scaffold.

bioRxiv · Apr 10, 2020Bioengineering