Apobec-Mediated Retroviral Hypermutation In Vivo is Dependent on Mouse Strain
H. Byun, G. B. Singh, W. K. Xu, P. Das, A. Reyes, A. Battenhouse, D. C. Wylie, M. M. Lozano, J. P. Dudley
This study shows that Rem protein in B6 mice affects tumorigenesis independently of Apobec-mediated proviral hypermutation, with TBLV-SD causing more tumors than TBLV-WT.
bioRxiv · Nov 2, 2023 · PreprintMicrobiology