Author

D. C. Wylie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

D. Arasappan· 2 shared D. Ghosh· 2 shared J. Leal· 2 shared R. Mohanty· 2 shared X. Liu· 2 shared X. Peng· 2 shared A. Battenhouse· 1 shared A. Reyes· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBioengineering

D. Arasappan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Apobec-Mediated Retroviral Hypermutation In Vivo is Dependent on Mouse Strain

H. Byun, G. B. Singh, W. K. Xu, P. Das, A. Reyes, A. Battenhouse, D. C. Wylie, M. M. Lozano, J. P. Dudley

This study shows that Rem protein in B6 mice affects tumorigenesis independently of Apobec-mediated proviral hypermutation, with TBLV-SD causing more tumors than TBLV-WT.

bioRxiv · Nov 2, 2023 · PreprintMicrobiology

Massively Parallel Selection of NanoCluster Beacons

Y.-A. Kuo, C. Jung, Y.-A. Chen, H.-C. Kuo, O. S. Zhao, T. D. Nguyen, J. R. Rybarski, S. Hong, Y.-I. Chen, D. C. Wylie, J. A. Hawkins, J. N. Walker, S. W. Shields, J. S. Brodbelt, J. T. Petty, , H.-C. Yeh

The paper develops a high-throughput method to screen and design multicolor NanoCluster Beacons using NGS chips and machine learning.

bioRxiv · Dec 4, 2021Bioengineering

A combinatorial biomolecular strategy to identify peptides for improved transport across the sputum of cystic fibrosis patients and the underlying epithelia

J. Leal, X. Liu, X. Peng, R. Mohanty, D. Arasappan, D. C. Wylie, S. H. Schwartz, J. J. Fullmer, B. C. McWilliams, H. D. Smyth, D. Ghosh

The paper identifies peptides that enhance drug delivery through mucus and epithelial barriers in CF patients using phage libraries and sequencing.

bioRxiv · Jun 4, 2019 · PreprintBioengineering

Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment

R. Mohanty, X. Liu, J. Y. Kim, X. Peng, S. Bhandari, J. Leal, D. Arasappan, D. C. Wylie, T. Dong, D. Ghosh

The paper identifies a peptide coating that enhances nanoparticle diffusion through the tumor microenvironment by screening phage libraries and testing transport in vitro and ex vivo.

Nanoscale · Jan 1, 2019Peer-reviewedBioengineering