Distinct Solubility and Cytotoxicity Regimes of Paclitaxel-Loaded Cationic Liposomes at Low and High Drug Content Revealed by Kinetic Phase Behavior and Cancer Cell Viability Studies
V. M. Steffes, M. M. Murali, Y. Park, B. J. Fletcher, K. Ewert, C. R. Safinya
This paper investigates the solubility and cytotoxicity of paclitaxel-loaded cationic liposomes at different drug contents, revealing nonmonotonic efficacy patterns linked to kinetic phase behavior.
bioRxiv · Jun 23, 2017Biophysics