Author

B. J. Fletcher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

C. R. Safinya· 2 shared C. Song· 1 shared C. Tchounwou· 1 shared H. P. Miller· 1 shared K. Ewert· 1 shared L. Wilson· 1 shared M. C. Choi· 1 shared M. M. Murali· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

C. R. Safinya

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2 papers

Recent·Most cited

Complexes of tubulin oligomers and tau form an intervening network cross-bridging microtubules into bundles

P. Kohl, C. Song, B. J. Fletcher, R. L. Best, C. Tchounwou, X. G. Arceo, P. J. Chung, H. P. Miller, L. Wilson, M. C. Choi, Y. Li, S. C. Feinstein, C. R. Safinya

The paper identifies an intervening network of tubulin-tau complexes that cross-link microtubules into bundles, revealing a new role for tubulin in stabilizing MT fascicles and preventing tau leakage in neurodegeneration.

bioRxiv · Jul 18, 2022 · PreprintBiophysics

Distinct Solubility and Cytotoxicity Regimes of Paclitaxel-Loaded Cationic Liposomes at Low and High Drug Content Revealed by Kinetic Phase Behavior and Cancer Cell Viability Studies

V. M. Steffes, M. M. Murali, Y. Park, B. J. Fletcher, K. Ewert, C. R. Safinya

This paper investigates the solubility and cytotoxicity of paclitaxel-loaded cationic liposomes at different drug contents, revealing nonmonotonic efficacy patterns linked to kinetic phase behavior.

bioRxiv · Jun 23, 2017Biophysics