Competition of Charge-Mediated and Specific Binding by Peptide-Tagged Cationic Liposome-DNA Nanoparticles In Vitro and In Vivo
E. Wonder, L. Simon-Gracia, P. Scodeller, R. N. Majzoub, V. R. Kotamraju, K. Ewert, T. Teesalu, C. R. Safinya
This study investigates how peptide density and charge affect the binding and uptake of cationic liposome-DNA nanoparticles by cancer cells and evaluates their tumor selectivity in vivo.
bioRxiv · Dec 20, 2017Biophysics