Author

M. M. Sarwal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 5 Organism:human· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

I. Damm· 3 shared M. Kerwin· 3 shared P. Rashmi· 3 shared T. Sigdel· 3 shared D. Rychkov· 2 shared M. Sirota· 2 shared S. Sur· 2 shared T. K. Sigdel· 2 shared

Activity by Year

2022-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

I. Damm

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.

P. Rashmi, T. K. Sigdel, D. Rychkov, I. Damm, A. A. da Silva, F. Vincenti, A. L. Lourenco, C. S. Craik, J. Reiser, M. M. Sarwal

This paper investigates how circulating factors like suPAR and CD40 autoantibodies induce podocyte injury in FSGS and identifies therapeutic targets for rFSGS.

Annals of Translational Medicine · Jun 1, 2023Peer-reviewedImmunology

Genetic deletion and pharmacologic inhibition of FcER1 reduces renal injury in mouse models of diabetic nephropathy.

P. Rashmi, A. A. Silva, T. Sigdel, I. Damm, A. L. F. Gouvea, S. Koliwad, V. Walavalkar, S. Hakroush, M. M. Sarwal

This study shows that reducing FcER1 signaling in mouse models of diabetic nephropathy decreases proteinuria and kidney damage.

bioRxiv · Sep 10, 2022 · PreprintImmunology

Plasma Proteome Perturbation for CMV DNAemia in Kidney Transplantation

T. Sigdel, P. Boada, M. Kerwin, P. Rashmi, D. Gjertson, M. Rossetti, S. Sur, D. Munar, J. Cimino, R. Ahn, H. Pickering, S. Sen, R. Parmar, B. Fatou, H. Steen, , CMV Systems Immunobiology Group

The paper identifies plasma proteomic changes associated with CMV DNAemia in kidney transplant recipients, revealing biomarkers for disease prediction and immune pathway insights.

bioRxiv · Aug 25, 2022 · PreprintImmunology

Perturbations of the T-cell immune repertoire in kidney transplant rejection

T. Sigdel, P. A. Fields, J. Liberto, I. Damm, M. Kerwin, J. Hood, P. Towfighi, M. Sirota, H. Robins, M. M. Sarwal

This study examines T-cell repertoire changes in kidney transplant recipients to understand rejection mechanisms, finding lower pre-transplant T-cell fractions and higher TCR turnover during acute rejection.

bioRxiv · Aug 24, 2022Immunology

Novel Mechanism for Tubular Injury in Nephropathic Cystinosis

S. Sur, M. Kerwin, S. Pineda, P. Sansanwal, T. K. Sigdel, M. Sirota, M. M. Sarwal

This study identifies ATP6V0A1 downregulation in cystinosis as a key factor in tubular injury, showing that antioxidants like astaxanthin can restore mitochondrial function and autophagosome turnover.

bioRxiv · May 13, 2022Cell Biology

Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses

T. Hagan, B. Gerristen, L. E. Tomalin, S. Fourati, M. P. Mule, D. G. Chawla, D. Rychkov, E. Henrich, H. E. Miller, J. Diray-Arce, P. Dunn, A. Lee, The Human Immunology Project Consortium (HIPC), O. Levy, R. Gottardo, , B. Pulendran

The paper integrates transcriptional data from 13 vaccines to identify a time-adjusted signature predicting antibody responses across different vaccines.

bioRxiv · Apr 20, 2022Immunology