Author

H. Steen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 6 Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 8 Research Focus:differential expression· 7 Assay:proteomics· 6 Research Focus:cell type annotation· 5 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2

Frequent Co-Authors

B. Fatou· 5 shared K. K. Smolen· 4 shared O. Levy· 4 shared A. Kentsis· 2 shared A. Ozonoff· 2 shared E. Mullen· 2 shared E. Perlman· 2 shared I. MacArthur· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

B. Fatou

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants

J. P. Gygi, C. Maguire, R. K. Patel, P. Shinde, A. Konstorum, C. P. Shannon, L. Xu, A. Hoch, N. Jayavelu, IMPACC Network, E. K. Haddad, E. F. Reed, M. Kraft, G. A. McComsey, J. Metcalf, , Pete

This study identifies immune programs linked to COVID-19 severity and mortality through longitudinal multi-omics analysis of 1,152 hospitalized patients.

bioRxiv · Nov 3, 2023Immunology

Early cellular and molecular signatures correlate with severity of West Nile Virus infection

H.-J. Lee, Y. Zhao, I. Fleming, S. Mehta, X. Wang, B. Vander Wyk, S. E. Ronca, H. Kang, C.-H. Chou, B. Fatou, K. K. Smolen, O. Levy, C. B. Clish, R. J. Xavier, H. Steen, , R. R. Montgomery

The paper identifies cellular and molecular signatures associated with varying severities of West Nile Virus infection using multi-omics analysis of immune responses.

bioRxiv · May 14, 2023Immunology

Plasma Proteome Perturbation for CMV DNAemia in Kidney Transplantation

T. Sigdel, P. Boada, M. Kerwin, P. Rashmi, D. Gjertson, M. Rossetti, S. Sur, D. Munar, J. Cimino, R. Ahn, H. Pickering, S. Sen, R. Parmar, B. Fatou, H. Steen, , CMV Systems Immunobiology Group

The paper identifies plasma proteomic changes associated with CMV DNAemia in kidney transplant recipients, revealing biomarkers for disease prediction and immune pathway insights.

bioRxiv · Aug 25, 2022 · PreprintImmunology

Epigenetic Memory of COVID-19 in Innate Immune Cells and Their Progenitors

J. G. Cheong, A. Ravishankar, S. Sharma, C. Parkhurst, D. Nehar-Belaid, S. Ma, L. Paddock, B. Fatou, E. Karakaslar, A. Thibodeau, M. Bale, V. Kartha, J. Yee, M. Y. Mays, L. Leyre, , S. Josefowicz

The paper identifies sustained epigenomic changes in hematopoietic stem and progenitor cells after COVID-19, which influence innate immune cell function and inflammation.

bioRxiv · Feb 9, 2022Immunology

Determinants of precocious B-cell aging in European adolescences living with perinatally acquired HIV-1 after over 10 years of suppressive therapy

A. Ruggiero, G. R. Pascucci, N. Cotugno, S. Dominguez-Rodriguez, R. Stefano, A. Tagarro Garcia, P. Rojo, C. Foster, A. Bamford, A. De Rossi, E. Nastouli, K. Nigel, M. Elena, B. Fatou, K. K. Smolen, , included in the manuscript

This study identifies factors associated with precocious B-cell aging in adolescents with perinatally acquired HIV on long-term suppressive therapy, linking them to immune dysfunction and reduced vaccine response.

bioRxiv · Nov 11, 2021 · PreprintImmunology

Proteomics on longitudinal serum samples differentiates localized and disseminated Lyme disease

B. Fatou, K. K. Smolen, A. A. Belperron, Z. Wurie, S. Kleinstein, R. Montgomery, O. Levy, L. K. Bockenstedt, H. Steen

This study uses serum proteomics to identify biomarkers distinguishing localized and disseminated Lyme disease stages.

bioRxiv · Nov 18, 2020 · PreprintImmunology

Prohibitin is a prognostic marker of relapse and therapeutic target to block chemotherapy resistance in Wilms tumor

M. V. Ortiz, S. Ahmed, M. Burns, A. G. Henssen, T. Hollmann, I. MacArthur, S. Gunasekerea, L. Gaewsky, G. Bradwin, J. Ryan, A. Letai, Y. He, A. Naranjo, Y.-Y. Chi, M. LaQuaglia, , A. Kentsis

This study identifies prohibitin as a urine biomarker for Wilms tumor relapse and shows it promotes chemotherapy resistance by disrupting mitochondrial apoptosis.

bioRxiv · Dec 30, 2018Cancer Biology

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

A. Henssen, R. Koche, J. Zhuang, E. Jiang, C. Reed, A. Eisenberg, E. Still, I. MacArthur, E. Rodriguez-Fos, S. Gonzalez, M. Puiggros, A. Blackford, C. Mason, E. De Stanchina, M. Gonen, , A. Kentsis

This study identifies PGBD5 as an oncogenic DNA transposase in rhabdoid tumors, causing site-specific genomic rearrangements through PSS sequences and end-joining repair.

bioRxiv · Feb 23, 2017Cancer Biology