The evolving systemic biomarker milieu in obese ZSF1 rat model of human cardiometabolic syndrome: Characterization of the model and cardioprotective effect of GDF15
M. Stolina, X. Luo, D. Dwyer, C.-Y. Han, R. Chen, Y. Zhang, Y. Xiong, Y. Chen, J. Yin, B. Ason, C. Hale, M. M. Veniant
This study characterizes an obese ZSF1 rat model of cardiometabolic syndrome and shows that GDF15 treatment reduces metabolic markers and improves cardiac function.
bioRxiv · Mar 20, 2020Physiology