Author

M. M. Zhu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Z. Dai· 3 shared B. Liu· 2 shared D. Yi· 2 shared J. Dai· 2 shared Y. Peng· 2 shared Y. Zhao· 2 shared A. Feng· 1 shared C. Gao· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersPhysiology

Z. Dai

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Unexpected Role of GCN2 Kinase Activation in Mediating Pulmonary Vascular Remodeling and Pulmonary Arterial Hypertension

M. M. Zhu, J. Dai, Z. Dai, Y. Peng, Y.-Y. Zhao

This study shows GCN2 kinase activation in hypoxia mediates pulmonary vascular remodeling and PAH via Edn1, suggesting GCN2 as a therapeutic target for PAH.

bioRxiv · Sep 5, 2023 · PreprintPhysiology

Loss of Endothelial HIF-Prolyl hydroxylase 2 (PHD2) Induces Cardiac Hypertrophy and Fibrosis

Z. Dai, J. Cheng, B. Liu, D. Yi, A. Feng, T. Wang, C. Gao, Y. Wang, M. M. Zhu, X. Zhang, Y. Zhao

This study shows that loss of endothelial PHD2 causes cardiac hypertrophy and fibrosis via HIF-2, and PHD2 is reduced in human cardiomyopathy.

Journal of the American Heart Association · Nov 16, 2021Peer-reviewedPhysiology

Endothelial PHD2 Deficiency Induces Nitrative Stress via Suppression of Caveolin-1 in Pulmonary Arterial Hypertension

B. Liu, Y. Peng, D. Yi, J. Dai, R. Vanderpool, M. M. Zhu, Z. Dai, Y. Zhao

This study shows that endothelial PHD2 deficiency leads to nitrative stress via suppression of Caveolin-1, contributing to pulmonary arterial hypertension and vascular remodeling.

bioRxiv · Sep 24, 2021Physiology