MUC5AC drives COPD exacerbation severity through amplification of virus-induced airway inflammation
A. Singanayagam, J. Footitt, B. T. Kasdorf, M. Marczynski, M. T. Cross, L. J. Finney, M.-B. Trujillo Torralbo, M. Calderazzo, J. Zhu, J. Aniscenko, T. B. Clarke, P. L. Molyneaux, N. W. Bartlett, M. F. Moffatt, W. O. Cookson, , S. L. Johnston
This study identifies MUC5AC as a driver of COPD exacerbation severity by amplifying virus-induced airway inflammation through ATP release.
bioRxiv · Jul 22, 2019Immunology