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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
N. Hara, D. S. Raclawska, L. E. Morgan, J. C. Needell, L. Dao, A. Kato, A. M. Jaramillo, P. S. Hume, F. Holguin, W. J. Janssen, E. K. Vladar, C. M. Evans
This study identifies fucosyltransferase 2 (Fut2) as essential for mucin fucosylation, which contributes to allergic airway hyperreactivity and mucus obstruction in mice.
bioRxiv · May 10, 2024Physiology
T. Ilani, N. Reznik, N. Yeshaya, T. Feldman, P. Vilela, Z. Lansky, G. Javitt, M. Shemesh, O. Brenner, Y. Elkis, N. Varsano, N. Murray, P. Azadi, A. M. Jaramillo, C. M. Evans, D. Fass
This study shows that QSOX1 regulates sialylation of the colon glycome by forming disulfides in Golgi glycosyltransferases, not by catalyzing mucin crosslinking.
bioRxiv · May 3, 2022 · PreprintCell Biology
C. M. Evans, M. Phillips, K. L. Malone, M. Tonelli, G. Cornilescu, C. Cornilescu, S. Holton, M. Gorjanacz, L. Wang, S. Carlson, J. C. Gay, J. C. Nix, B. Demeler, J. L. Markley, K. C. Glass
This study identifies how the ATAD2 bromodomain recognizes di-acetylated histone tails through residue-specific interactions and confirms its monomeric state using biophysical techniques.
bioRxiv · Jul 23, 2021Biochemistry
J. T. Lloyd, K. McLaughlin, M. Y. Lubula, J. C. Gay, A. Dest, C. Gao, M. Phillips, M. Tonelli, G. Cornilescu, M. R. Marunde, C. M. Evans, S. P. Boyson, S. Carlson, M.-C. Keogh, J. L. Markley, , K. C. Glass
This study investigates the ligand specificity of the ATAD2B bromodomain, showing it binds mono- and di-acetylated histones and identifies structural features critical for this recognition.
bioRxiv · May 12, 2020 · PreprintBiochemistry
B. Korber, W. Fischer, S. G. Gnanakaran, H. Yoon, J. Theiler, W. Abfalterer, B. Foley, E. E. Giorgi, T. Bhattacharya, M. D. Parker, D. G. Partridge, C. M. Evans, T. de Silva, C. C. LaBranche, D. C. Montefiori, Sheffield COVID-19 Genomics Group
The paper develops a pipeline to track SARS-CoV-2 mutations in the Spike protein, identifying D614G as a rapidly spreading mutation with potential implications for transmission and immune evasion.
bioRxiv · Apr 29, 2020Evolutionary Biology
J. O. Obi, M. Y. Lubula, G. Cornilescu, A. Henrickson, K. McGuire, C. M. Evans, M. Phillips, S. P. Boyson, B. Demeler, J. L. Markley, K. C. Glass
This study identifies the BRPF1 bromodomain as a selective reader of di-acetyllysine modifications on histone H4 and characterizes its binding preferences and mechanisms.
bioRxiv · Feb 13, 2020Biochemistry
L. E. Morgan, S. K. Shenoy, D. Raclawska, N. A. Emezienna, V. L. Richardson, N. Hara, A. Q. Harder, H. M. El-Batal, C. M. Magin, D. E. G. Villalon, G. Duncan, J. S. Hanes, J. S. Suk, D. J. Thornton, F. Holguin, , C. M. Evans
This study shows that reducing disulfide bonds in mucins reverses mucus dysfunction in asthma by improving mucociliary clearance and reducing airway hyperreactivity.
bioRxiv · Sep 14, 2019Physiology
A. Singanayagam, J. Footitt, B. T. Kasdorf, M. Marczynski, M. T. Cross, L. J. Finney, M.-B. Trujillo Torralbo, M. Calderazzo, J. Zhu, J. Aniscenko, T. B. Clarke, P. L. Molyneaux, N. W. Bartlett, M. F. Moffatt, W. O. Cookson, , S. L. Johnston
This study identifies MUC5AC as a driver of COPD exacerbation severity by amplifying virus-induced airway inflammation through ATP release.
bioRxiv · Jul 22, 2019Immunology
A. M. Jaramillo, L. Piccotti, W. V. Velasco, A. S. Huerta Delgado, Z. Azzegagh, F. Chung, U. Nazeer, J. Farooq, J. Brenner, J. Parker-Thornburg, B. L. Scott, C. M. Evans, R. Adachi, A. R. Burns, S. M. Kreda, , B. F. Dickey
The paper identifies distinct roles of Munc18 isoforms in baseline and stimulated airway mucin secretion, showing Munc18b's protective role in asthma and cystic fibrosis models.
bioRxiv · Oct 24, 2018Cell Biology