Author

M. Nadler-Holly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

F. Liu· 2 shared A. Eggert· 1 shared A. Sieber· 1 shared A. Singh· 1 shared B. Klinger· 1 shared C. K. Frese· 1 shared D. Beule· 1 shared D. Fiedler· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

F. Liu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pyrophosphoproteomics: extensive protein pyrophosphorylation revealed in human cell lines

J. A. M. Morgan, A. Singh, L. Kurz, M. Nadler-Holly, M. Penkert, E. Krause, F. Liu, R. Bhandari, D. Fiedler

This study identifies endogenous protein pyrophosphorylation in human cell lines using a tailored pyrophosphoproteomics workflow, revealing its role in rDNA transcription regulation.

bioRxiv · Nov 11, 2022 · PreprintBiochemistry

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance

M. Dorel, B. Klinger, T. Mari, J. Toedling, E. Blanc, M. Nadler-Holly, M. Ziehm, A. Sieber, F. Hertwig, D. Beule, A. Eggert, J. H. Schulte, M. Selbach, N. Bluthgen

This study identifies feedback-mediated resistance to MEK inhibitors in neuroblastoma and shows that combining MEK with RAF or IGFR inhibitors can overcome resistance.

bioRxiv · Jun 14, 2021Cancer Biology

Expanding the depth and sensitivity of cross-link identification by differential ion mobility using FAIMS

L. Schnirch, M. Nadler-Holly, S.-W. Siao, C. K. Frese, R. Viner, F. Liu

This study improves cross-link identification in XL-MS by using FAIMS to enhance separation and sensitivity, increasing identification rates by 23-56%.

bioRxiv · Apr 23, 2020Biochemistry