Author

M. Ziehm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:Drosophila· 1

Frequent Co-Authors

M. Selbach· 2 shared A. Eggert· 1 shared A. F. Florez· 1 shared A. Sieber· 1 shared B. Klinger· 1 shared B. Nicke· 1 shared C. Herrmann· 1 shared C. Shao· 1 shared

Activity by Year

2016-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

M. Selbach

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MYCN mediates cysteine addiction and sensitizes to ferroptosis

H. Alborzinia, A. F. Florez, S. Gogolin, L. M. Brueckner, C. Shao, M. Gartlgruber, M. Nadler Holly, M. Ziehm, F. Paul, S. Steinhauser, E. Bell, M. Shaikhkarami, S. Hartlieb, D. Dreidax, E. M. Hess, , F. Westermann

This study shows MYCN promotes cysteine addiction and ferroptosis resistance in neuroblastoma, identifying therapeutic targets for ferroptosis induction.

bioRxiv · Aug 10, 2021 · PreprintCancer Biology

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance

M. Dorel, B. Klinger, T. Mari, J. Toedling, E. Blanc, M. Nadler-Holly, M. Ziehm, A. Sieber, F. Hertwig, D. Beule, A. Eggert, J. H. Schulte, M. Selbach, N. Bluthgen

This study identifies feedback-mediated resistance to MEK inhibitors in neuroblastoma and shows that combining MEK with RAF or IGFR inhibitors can overcome resistance.

bioRxiv · Jun 14, 2021Cancer Biology

Drug repurposing for ageing research using model organisms

M. Ziehm, S. Kaur, D. K. Ivanov, P. J. Ballester, D. Marcus, L. Partridge, J. M. Thornton

This study ranks 743 drug-like compounds for their potential to modulate ageing in C. elegans and Drosophila using genetic, structural, and pharmacological data.

bioRxiv · Dec 22, 2016Pharmacology & Toxicology