Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights from Experimental and Molecular Dynamics Simulations Studies
D. S. J. Ting, J. Li, C. S. Verma, E. T. L. Goh, M. Nubile, L. Mastropasqua, D. G. Said, R. W. Beuerman, R. Lakshminarayanan, I. Mohammed, H. S. Dua
This study evaluates the synergistic interaction of CaD23 with antibiotics and identifies its membrane-permeabilizing mechanism through experimental and molecular dynamics simulations.
bioRxiv · Jun 26, 2021Microbiology