T. Aung

Iris Morphological and Biomechanical Factors Influencing Angle Closure During Pupil Dilation

This study uses finite element analysis to identify iris and anterior chamber factors influencing angle closure during pupil dilation, finding that smaller anterior chamber depth and width, and larger iris thickness and convexity increase angle narrowing.

How Myopia and Glaucoma Influence the Biomechanical Susceptibility of the Optic Nerve Head

This study compares biomechanical strain in optic nerve heads under different conditions across groups with varying myopia and glaucoma status, finding significant differences in strain levels.

The Structural Layers of the Porcine Iris Exhibit Inherently Different Biomechanical Properties

This study isolates porcine iris tissues and measures their biomechanical properties, finding the stroma more permeable and less rigid than the dilator muscle.

Enhanced Complex Stability and Optimal JAK Geometry are Pivotal for a Potent Type III Interferon Response

This study identifies that optimizing JAK-JAK geometry enhances type III IFN signaling potency by 2-3 logs, offering insights into cytokine signaling and therapeutic development.

Integrative deep learning analysis improves colon adenocarcinoma patient stratification at risk for mortality

This paper develops an integrative deep learning model combining image, clinical, and genomic data to improve risk stratification for colon adenocarcinoma patients, showing better performance than models using single data types.

Differing Associations between Optic Nerve Head Strains and Visual Field Loss in Normal- and High-Tension Glaucoma Subjects

This study examines the relationship between optic nerve head strains under IOP elevation and retinal sensitivity in glaucoma patients, finding stronger associations in high-tension glaucoma compared to normal-tension glaucoma.

Changes in Iris Stiffness and Permeability in Primary Angle Closure Glaucoma

This study compares iris biomechanical properties between healthy individuals and PACG patients, finding higher stiffness and lower permeability in PACG.

Hybrid Derivative of Cathelicidin and Human Beta Defensin-2 Against Gram-Positive Bacteria: A Novel Approach for the Treatment of Bacterial Keratitis

This paper develops a hybrid antimicrobial peptide (CaD23) from human-derived host defense peptides, showing high efficacy against Gram-positive bacteria and reduced antimicrobial resistance compared to amikacin.

Effect of Changing Heart Rate on the Ocular Pulse and Dynamic Biomechanical Behavior of the Optic Nerve Head

The paper models how changes in heart rate affect ocular pulse and biomechanical properties of the optic nerve head, finding decreased pulse amplitude and increased stiffness with higher heart rates.

Optic Nerve Tortuosity and Globe Proptosis in Normal and Glaucoma Subjects

The paper compares optic nerve tortuosity and globe proptosis between glaucoma and normal subjects using MRI, finding greater tortuosity in normal eyes during adduction and higher proptosis in glaucoma subjects in primary gaze.