Single particle profiler for measuring content and properties of nano-sized bioparticles
T. Sych, J. Schlegel, H. Barriga, M. Ojansivu, L. Hanke, F. Weber, B. Bostancioglu, K. Ezzat, H. Stangl, B. Plochberger, J. Laurencikiene, S. El Andaloussi, D. Furth, M. Stevens, E. Sezgin
The paper introduces a high-throughput method called single particle profiler (SPP) to analyze content and biophysical properties of nanoscale bioparticles, demonstrating its application on mRNA encapsulation, viral binding, and biophysical heterogeneity.
bioRxiv · Jul 8, 2022Biophysics