Author

S. EL Andaloussi

Karolinska Institutet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 3 Biophysics· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

D. Gupta· 3 shared D. R. Mamand· 3 shared A. Dev· 2 shared A. Gorgens· 2 shared A. M. Zickler· 2 shared F. Stridfeldt· 2 shared G. Zhou· 2 shared H. Zhou· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

D. Gupta

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Posterior specification of multi-lineage axial assembloids from human pluripotent stem cells.

Nigel Kee, Mélanie Lebœuf, S Gómez, Charles Petitpré, Irene Mei, Salim Benlefki, Daniel W. Hagey, JM Dias, François Lallemend, S. EL Andaloussi, Johan Ericson, Eva Hedlund

This paper describes a protocol to generate human posterior axial assembloids from pluripotent stem cells, demonstrating multi-lineage differentiation and tissue complexity.

bioRxiv · Aug 29, 2024 · PreprintCell Biology

Surface adhesion and membrane fluctuations influence the elastic modulus of extracellular vesicles

F. Stridfeldt, H. Kylhammar, P. Metem, V. Pandey, V. Agrawal, A. Gorgens, D. R. Mamand, O. Gustafsson, S. El Andaloussi, D. Mitra, A. Dev

This study develops a method to accurately measure the elastic modulus of extracellular vesicles, showing that surface adhesion and membrane fluctuations significantly affect the results.

bioRxiv · Feb 7, 2024 · PreprintBiophysics

Extracellular vesicle-mediated promotion of myogenic differentiation is dependent on dose, collection media composition, and isolation method

B. Hanson, M. Conceicao, Y. Lomonosova, I. Mager, P. L. Puri, S. EL Andaloussi, M. J. A. Wood, T. C. Roberts

This study shows that extracellular vesicles promote myogenic differentiation in C2C12 cells, but their effectiveness depends on dose, collection media, and isolation method.

Molecular Therapy - Nucleic Acids · Sep 1, 2023Peer-reviewedCell Biology

Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery

X. Liang, D. Gupta, J. Xie, E. V. Wonterghem, L. V. Hoecke, J. Hean, Z. Niu, O. P. B. Wiklander, W. Zheng, R. J. Wiklander, R. He, D. R. Mamand, J. Bost, G. Zhou, H. Zhou, , S. EL Andaloussi

This paper develops VEDIC and VFIC systems for efficient intracellular protein delivery using engineered extracellular vesicles, achieving high recombination and genome editing efficiency in vitro and in vivo.

bioRxiv · Apr 30, 2023 · PreprintBioengineering

Novel endogenous engineering platform for robust loading and delivery of functional mRNA by extracellular vesicles

A. M. Zickler, X. Liang, D. Gupta, D. Mamand, M. de Luca, G. Corso, L. Errichelli, J. Hean, T. Sen, O. M. Elsharkasy, N. Kamei, Z. Niu, G. Zhou, H. Zhou, S. Roudi, , S. EL Andaloussi

This paper develops an mRNA delivery system using extracellular vesicles engineered with RNA-binding domains and fusogenic moieties, showing improved efficacy in a melanoma model.

bioRxiv · Mar 17, 2023Bioengineering

Single particle profiler for measuring content and properties of nano-sized bioparticles

T. Sych, J. Schlegel, H. Barriga, M. Ojansivu, L. Hanke, F. Weber, B. Bostancioglu, K. Ezzat, H. Stangl, B. Plochberger, J. Laurencikiene, S. El Andaloussi, D. Furth, M. Stevens, E. Sezgin

The paper introduces a high-throughput method called single particle profiler (SPP) to analyze content and biophysical properties of nanoscale bioparticles, demonstrating its application on mRNA encapsulation, viral binding, and biophysical heterogeneity.

bioRxiv · Jul 8, 2022Biophysics

Multiparametric Profiling of Single Nanoscale Extracellular Vesicles by Combined Atomic Force and Fluorescence Microscopy: Correlation and Heterogeneity in Their Molecular and Biophysical Features

S. Cavallaro, F. Pevere, F. Stridfeldt, A. Görgens, C. Paba, S. S. Sahu, D. R. Mamand, D. Gupta, S. EL Andaloussi, J. Linnros, A. Dev

This study uses combined atomic force and fluorescence microscopy to analyze molecular and biophysical features of single extracellular vesicles from different cell lines, revealing correlations and heterogeneity in their properties.

bioRxiv · Jan 22, 2021Bioengineering