M. Oravcova

The Nse5/6-like SIMC1-SLF2 Complex Localizes SMC5/6 to Viral Replication Centers

This paper identifies SIMC1 and SLF2 as novel subunits forming Nse5/6-like complexes that regulate SMC5/6 localization to viral replication centers and DNA damage sites.

Activation of FAM111A Protease Induces Defects in Nuclear Function that Likely Underlie its Roles in Disease and Viral Restriction

This study shows FAM111A protease mutants cause nuclear dysfunction linked to disease and viral restriction.