Author

M. Oresic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 6 Organism:human· 5 Approach:statistical model· 5 Research Focus:differential expression· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

T. Hyotylainen· 6 shared S. Lamichhane· 4 shared A. M. Dickens· 3 shared E. Kemppainen· 3 shared H. Hyoty· 2 shared H. Siljander· 2 shared J. Ilonen· 2 shared J. Toppari· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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6 shared papersBiochemistry

T. Hyotylainen

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Author profile →

6 papers

Recent·Most cited

Comparative metabolomics and microbiome analysis of Ethanol vs. OMNImet/gene GUT fecal stabilization

H. Isokaanta, L. Pinto da Silva, N. Karu, T. Kallonen, A. K. Aatsinki, T. Hankemeier, L. Schimmel, E. Diaz, T. Hyotylainen, P. C. Dorrestein, R. Knight, M. Oresic, R. K. Daouk, A. M. Dickens, S. Lamichhane

This study compares the stability of fecal metabolome and microbiome using 95% ethanol and commercial kits under different storage conditions, finding comparable results to flash freezing.

bioRxiv · Aug 29, 2023 · PreprintBiochemistry

Dynamics of lipidome in a colon simulator

M. Krakstrom, M. A. Alves, A. M. Dickens, S. D. Forssten, A. C. Ouwehand, T. Hyotylainen, M. Oresic, S. Lamichhane

This study examines lipid dynamics in an in vitro colon simulator, showing vessel position and time affect lipid profiles, with changes in phosphatidylcholines, sphingomyelins, triacylglycerols, and endocannabinoids.

bioRxiv · Dec 13, 2022 · PreprintBiochemistry

Quantitative analysis and genome-scale modeling of human CD4+ T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathways

P. Sen, S. B. A. Andrabi, T. Buchacher, M. M. Khan, U. Ullah, T. Lindeman, M. Alves Amaral, V. Hinkkanen, E. Kemppainen, A. M. Dickens, O. Rasool, T. Hyotylainen, R. Lahesmaa, M. Oresic

This study uses genome-scale modeling and lipidomics to show that glycosphingolipid pathways are specifically regulated in Th17 cells during differentiation and are critical for their effector functions.

bioRxiv · Jan 29, 2021 · PreprintImmunology

Targeted Clinical Metabolomics Platform for the Stratification of Diabetic Patients

L. Ahonen, S. Jantti, T. Suvitaival, S. Thelaide, C. Risz, R. Kostiainen, P. Rossing, M. Oresic, T. Hyotylainen

The paper develops and validates a clinical metabolomics platform to stratify diabetic patients using 36 metabolite biomarkers from human plasma.

bioRxiv · Jun 9, 2019 · PreprintBiochemistry

Circulating Metabolites in Progression to Islet Autoimmunity and Type 1 Diabetes

S. Lamichhane, E. Kemppainen, K. Trost, H. Siljander, H. Hyoty, J. Ilonen, J. Toppari, R. Veijola, T. Hyotylainen, M. Knip, M. Oresic

The paper identifies unique metabolic profiles in children progressing to type 1 diabetes, showing early metabolic disturbances and changes associated with islet autoantibodies.

bioRxiv · Dec 16, 2018Biochemistry

Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes: Type 1 Diabetes Prediction and Prevention Study (DIPP)

S. Lamichhane, L. Ahonen, T. S. Dyrlund, E. Kemppainen, H. Siljander, H. Hyoty, J. Ilonen, J. Toppari, R. Veijola, T. Hyotylainen, M. Knip, M. Oresic

The paper identifies distinct lipidomic signatures in children progressing to islet autoimmunity or T1D, suggesting potential biomarkers for early detection.

bioRxiv · Apr 3, 2018Biochemistry