Author

E. Kemppainen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:metabolomics· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. Oresic· 3 shared T. Hyotylainen· 3 shared H. Hyoty· 2 shared H. Siljander· 2 shared J. Ilonen· 2 shared J. Toppari· 2 shared M. Knip· 2 shared R. Veijola· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBiochemistry

M. Oresic

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Separate Gut Plasma Cell Populations Produce Autoantibodies Against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis

S. Das, J. Stamnaes, E. Kemppainen, K. Hervonen, K. E. A. Lundin, N. Parmar, F. L. Jahnsen, J. Jahnsen, K. Lindfors, T. Salmi, R. Iversen, L. M. Sollid

The paper identifies separate gut plasma cell populations in DH patients producing autoantibodies specific to TG2 and TG3 with no cross-reactivity.

bioRxiv · May 31, 2023Immunology

Quantitative analysis and genome-scale modeling of human CD4+ T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathways

P. Sen, S. B. A. Andrabi, T. Buchacher, M. M. Khan, U. Ullah, T. Lindeman, M. Alves Amaral, V. Hinkkanen, E. Kemppainen, A. M. Dickens, O. Rasool, T. Hyotylainen, R. Lahesmaa, M. Oresic

This study uses genome-scale modeling and lipidomics to show that glycosphingolipid pathways are specifically regulated in Th17 cells during differentiation and are critical for their effector functions.

bioRxiv · Jan 29, 2021 · PreprintImmunology

Circulating Metabolites in Progression to Islet Autoimmunity and Type 1 Diabetes

S. Lamichhane, E. Kemppainen, K. Trost, H. Siljander, H. Hyoty, J. Ilonen, J. Toppari, R. Veijola, T. Hyotylainen, M. Knip, M. Oresic

The paper identifies unique metabolic profiles in children progressing to type 1 diabetes, showing early metabolic disturbances and changes associated with islet autoantibodies.

bioRxiv · Dec 16, 2018Biochemistry

Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes: Type 1 Diabetes Prediction and Prevention Study (DIPP)

S. Lamichhane, L. Ahonen, T. S. Dyrlund, E. Kemppainen, H. Siljander, H. Hyoty, J. Ilonen, J. Toppari, R. Veijola, T. Hyotylainen, M. Knip, M. Oresic

The paper identifies distinct lipidomic signatures in children progressing to islet autoimmunity or T1D, suggesting potential biomarkers for early detection.

bioRxiv · Apr 3, 2018Biochemistry