Integration of multi-omics data shows downregulation of mismatch repair, purin, and tublin pathways in AR-negative triple-negative chemotherapy-resistant breast tumors
X. Tang, K. J. Thompson, K. R. Kalari, J. P. Sinnwell, V. Suman, P. T. Vedell, S. A. McLaughlin, D. W. Northfelt, A. Moreno Aspitia, R. J. Gray, J. M. Carter, R. Weinshilboum, L. Wang, J. C. Boughey, M. P. Goetz
The paper identifies a 17-gene signature from post-NAC biopsies that shows downregulation of immune and pathway genes associated with TNBC recurrence.
bioRxiv · May 16, 2022 · PreprintCancer Biology