Author

M. Pfuhl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1 Organism:yeast· 1

Frequent Co-Authors

A. Alexandrovich· 1 shared A. Beavil· 1 shared A. Fukuzawa· 1 shared A. Holder· 1 shared A. L. Kho· 1 shared D. Koch· 1 shared D. Ngugi· 1 shared D. Werling· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Alexandrovich

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro

D. Koch, A. L. Kho, A. Fukuzawa, A. Alexandrovich, A. Beavil, M. Pfuhl, M. Rees, M. Gautel

The paper investigates obscurin GEF domains, showing they are phosphorylated by MST-family kinases but lack detectable nucleotide exchange activity towards Rho GTPases in vitro.

bioRxiv · Oct 14, 2022 · PreprintBiochemistry

Development of a yeast-based vaccine for Theileria parva infection in cattle

S. Goh, J. Kolakowski, A. Holder, M. Pfuhl, D. Ngugi, K. Ballingall, K. Tombacz, D. Werling

This paper develops a yeast-based vaccine for Theileria parva infection using recombinant antigens expressed on Saccharomyces cerevisiae, showing immune responses in mice and potential for oral application.

bioRxiv · Jan 30, 2021Immunology

Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

K. Pollock, M. Liu, M. Zaleska, M. Pfuhl, I. Collins, S. Guettler

This study identifies fragment molecules targeting tankyrase's substrate-binding ankyrin repeat domains through biophysical assays, offering potential new therapeutic approaches for cancer.

bioRxiv · Mar 4, 2019Biophysics