Author

M. R. Botchan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:protein sequence· 1

Frequent Co-Authors

J. A. Kao· 2 shared M. W. Parker· 2 shared A. T. Huang· 1 shared J. M. Berger· 1 shared J. M. M. Berger· 1 shared M. Bell· 1 shared M. Mir· 1 shared X. Darzacq· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

J. A. Kao

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2 papers

Recent·Most cited

Molecular determinants of phase separation for Drosophila DNA replication licensing factors

M. W. Parker, J. A. Kao, A. T. Huang, J. M. Berger, M. R. Botchan

This study identifies molecular mechanisms underlying phase separation in Drosophila DNA replication licensing factors, showing that DNA-bridging and hydrophobic interactions drive condensate formation and specificity.

bioRxiv · Apr 12, 2021Biophysics

A new class of disordered elements controls DNA replication through initiator self-assembly

M. W. Parker, M. Bell, M. Mir, J. A. Kao, X. Darzacq, M. R. Botchan, J. M. M. Berger

This study identifies a new class of disordered elements that drive liquid-liquid phase separation in DNA replication initiators in D. melanogaster.

bioRxiv · Apr 29, 2019Biochemistry