Author

M. Ratnaparkhe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. Ernst· 2 shared A. Jauch· 2 shared A. Korshunov· 2 shared M. Zapatka· 2 shared R. Kumar· 2 shared T. Kolb· 2 shared A. Pastorczak· 1 shared D. Haag· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

A. Ernst

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2 papers

Recent·Most cited

Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability

R. G. Parra, M. J. Przybilla, M. Simovic, H. Susak, M. Ratnaparkhe, J. K. Wong, V. Koerber, P. Mallm, M. Sill, T. Kolb, R. Kumar, N. Casiraghi, D. R. Ghasemi, K. K. Maass, K. W. Pajtler, , A. Ernst

This study analyzes single-cell multi-omics data from medulloblastoma to explore genomic and transcriptomic impacts of chromothripsis and its subclonal variation.

bioRxiv · Jun 25, 2021 · PreprintCancer Biology

Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors

M. Ratnaparkhe, J. Wong, P.-C. Wei, M. Hlevnjak, T. Kolb, D. Haag, Y. Paul, F. Devens, P. Northcott, D. T. Jones, M. Kool, A. Jauch, A. Pastorczak, W. Mlynarski, A. Korshunov, , A. Ernst

The paper identifies chromothripsis and chromoanasynthesis in tumors with DNA repair deficiencies and links them to MYC/MYCN amplification and therapeutic opportunities.

bioRxiv · May 4, 2018Cancer Biology