Author

K. W. Pajtler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Korshunov· 3 shared S. M. Pfister· 3 shared D. Kawauchi· 2 shared D. R. Ghasemi· 2 shared D. T. W. Jones· 2 shared K. K. Maass· 2 shared K. Okonechnikov· 2 shared M. Sill· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. Korshunov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

D. R. Ghasemi, K. Okonechnikov, A. Rademacher, S. Tirier, K. K. Maass, H. Schumacher, J. Sundheimer, B. Statz, A. S. Rifaioglu, K. Bauer, S. Schumacher, M. Bortolomeazzi, F. Giangaspero, K. J. Ernst, J. Saez-Rodriguez, , K. W. Pajtler

The paper uses single-cell transcriptomics to show how two compartments in medulloblastoma are connected through a migrating precursor stage, revealing spatial and developmental links between proliferating and differentiated tumor cells.

Nature Communications · Jan 8, 2024Peer-reviewedCancer Biology

Mapping pediatric brain tumors to their origins in the developing cerebellum

K. Okonechnikov, P. Joshi, M. Sepp, K. Leiss, I. Sarropoulos, F. Murat, M. Sill, P. Beck, K. C.-H. Chan, A. Korshunov, F. Sahm, M. Y. Deng, D. Sturm, J. DeSisto, A. M. Donson, , S. M. Pfister

The paper maps the cellular origins of three common pediatric brain tumors using a single-nucleus atlas and transcriptome data, identifying lineage-specific origins and potential therapeutic targets.

bioRxiv · Dec 19, 2021Cancer Biology

Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability

R. G. Parra, M. J. Przybilla, M. Simovic, H. Susak, M. Ratnaparkhe, J. K. Wong, V. Koerber, P. Mallm, M. Sill, T. Kolb, R. Kumar, N. Casiraghi, D. R. Ghasemi, K. K. Maass, K. W. Pajtler, , A. Ernst

This study analyzes single-cell multi-omics data from medulloblastoma to explore genomic and transcriptomic impacts of chromothripsis and its subclonal variation.

bioRxiv · Jun 25, 2021 · PreprintCancer Biology