M. Riera

Determinants of de novo mutations in extended pedigrees of 43 dog breeds

The paper investigates mutation rates in 43 dog breeds, finding stable rates influenced by parental age and breed-specific differences in mutation accumulation.

Mutationathon: towards standardization in estimates of pedigree-based germline mutation rates

The paper evaluates variation in germline mutation rate estimates across labs using a standardized pedigree of rhesus macaques, highlighting methodological differences and the need for standardization.

Cell Sex and Sex Hormones Modulate Kidney Glucose and Glutamine Metabolism in Health and Diabetes

This study shows that cell sex and sex hormones influence glucose and glutamine metabolism in kidney cells, with male cells showing increased metabolic stress and female cells showing better redox balance.

SARS-CoV-2 infection suppresses ACE2 function and antiviral immune response in the upper respiratory tract of infected patients

This study shows SARS-CoV-2 reduces ACE2 activity and antiviral gene expression in the upper respiratory tract, while initially increasing interferon-stimulated genes.

Epigenomic profiling of primate LCLs reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures

The paper profiles epigenomic features in primate LCLs to reveal evolutionary patterns of epigenetic activity in gene regulation.