Author

O. Zaslaver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

H. Rost· 3 shared A. Konvalinka· 2 shared C. M. McEvoy· 2 shared S. Clotet-Freixas· 2 shared A. B. Dart· 1 shared A. Boshart· 1 shared A. Finelli· 1 shared A. Isenbrandt· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

H. Rost

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bacterial ADP-heptose initiates a revival stem cell program in the intestinal epithelium

S. Goyal, C. X. Guo, A. Ranger, D. K. Tsang, O. Singh, C. F. Harrigan, O. Zaslaver, H. Rost, H. Y. Gaisano, S. Yuzwa, N. Gao, J. L. Wrana, D. J. Philpott, S. D. Gray-Owen, S. Girardin

This study shows that bacterial ADP-heptose triggers a revival stem cell program in the intestinal epithelium by inducing Paneth cell dedifferentiation and ISC loss.

bioRxiv · Jan 15, 2024 · PreprintCell Biology

Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity

C. M. McEvoy, J. M. Murphy, L. Zhang, S. Clotet-Freixas, J. A. Mathews, J. An, M. Karimzadeh, D. Pouyabahar, S. Su, O. Zaslaver, H. Rost, M. Arambewela, L. Y. Liu, S. Zhang, K. A. Lawson, , S. Q. Crome

This study profiles healthy human kidney cells from 19 donors to reveal sex-based transcriptional differences and tissue-specific immune features.

bioRxiv · Dec 9, 2021Immunology

Cell Sex and Sex Hormones Modulate Kidney Glucose and Glutamine Metabolism in Health and Diabetes

S. Clotet-Freixas, O. Zaslaver, C. Pastrello, M. Kotlyar, C. M. McEvoy, S. Farkona, A. Saha, A. Boshart, M. Chan, M. Riera, M. J. Soler, A. Isenbrandt, J. Lamontagne-Proulx, S. Pradeloux, K. Coulombe, , A. Konvalinka

This study shows that cell sex and sex hormones influence glucose and glutamine metabolism in kidney cells, with male cells showing increased metabolic stress and female cells showing better redox balance.

bioRxiv · Aug 23, 2021 · PreprintCell Biology