Author

S. Clotet-Freixas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Konvalinka· 5 shared C. M. McEvoy· 3 shared A. Boshart· 2 shared C. Pastrello· 2 shared H. Rost· 2 shared I. Jurisica· 2 shared M. Kotlyar· 2 shared O. Zaslaver· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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5 shared papersBioengineering

A. Konvalinka

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Biomimetic fractal topography enhances podocyte maturation in vitro

C. Liu, P. Aggarwal, K. T. Wagner, S. S. Landau, T. Cui, X. Song, L. Shamaei, N. Rafatian, Y. Zhao, S. Rodriguez-Ramirez, K. Morton, E. Virlee, C. Y. Li, D. Bannerman, S. Pascual-Gil, , M. Radisic

This study shows that biomimetic fractal topography improves podocyte maturation in vitro by enhancing marker expression, cell polarity, and ECM remodeling via YAP signaling.

bioRxiv · Mar 16, 2024Bioengineering

Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity

C. M. McEvoy, J. M. Murphy, L. Zhang, S. Clotet-Freixas, J. A. Mathews, J. An, M. Karimzadeh, D. Pouyabahar, S. Su, O. Zaslaver, H. Rost, M. Arambewela, L. Y. Liu, S. Zhang, K. A. Lawson, , S. Q. Crome

This study profiles healthy human kidney cells from 19 donors to reveal sex-based transcriptional differences and tissue-specific immune features.

bioRxiv · Dec 9, 2021Immunology

Cell Sex and Sex Hormones Modulate Kidney Glucose and Glutamine Metabolism in Health and Diabetes

S. Clotet-Freixas, O. Zaslaver, C. Pastrello, M. Kotlyar, C. M. McEvoy, S. Farkona, A. Saha, A. Boshart, M. Chan, M. Riera, M. J. Soler, A. Isenbrandt, J. Lamontagne-Proulx, S. Pradeloux, K. Coulombe, , A. Konvalinka

This study shows that cell sex and sex hormones influence glucose and glutamine metabolism in kidney cells, with male cells showing increased metabolic stress and female cells showing better redox balance.

bioRxiv · Aug 23, 2021 · PreprintCell Biology

AngioPlate - Biofabrication of perfusable complex tissues in multi-well plates with 4D subtractive manufacturing

S. Rajasekar, D. S. Y. Lin, F. Zhang, A. Sotra, A. Boshart, S. Clotet-Freixas, A. Liu, J. A. Hirota, S. Ogawa, A. Konvalinka, B. Zhang

The paper introduces a 4D subtractive manufacturing technique to create perfusable complex tissues in multi-well plates, enabling the fabrication of vascular networks and organ-specific structures.

bioRxiv · Aug 13, 2021 · PreprintBioengineering

Autoantibodies Against Ro/SS-A, CENP-B, and La/SS-B are Increased in Patients with Kidney Allograft Antibody-Mediated Rejection

S. Clotet-Freixas, M. Kotlyar, C. M. McEvoy, C. Pastrello, S. Rodriguez-Ramirez, S. Farkona, H. Cardinal, M. Dieude, M.-J. Hebert, Y. Li, O. Famure, P. Chen, S. J. Kim, E. Chan, I. Jurisica, , A. Konvalinka

The paper identifies increased levels of specific non-HLA autoantibodies in kidney transplant patients with antibody-mediated rejection.

bioRxiv · Dec 2, 2020Immunology