Flotillin-dependent lipid-raft microdomains are required for functional phagolysosomes against fungal infections
F. Schmidt, A. Thywissen, M. Röcker, C. Cunha, Z. Cseresnyes, H. Schmidt, S. Galiani, M. H. Gräler, G. Chamilos, J. F. Lacerda, A. Campos, C. Eggeling, T. Figge, T. Heinekamp, S. G. Filler, , A. A. Brakhage
This study shows that flotillin-dependent lipid rafts are essential for phagolysosomal function against fungal infections, with implications for human susceptibility to aspergillosis.
bioRxiv · Apr 12, 2019Microbiology