The crystal structure of nsp10-nsp16 heterodimer from SARS CoV-2 in complex with S-adenosylmethionine
M. Rosas Lemus, G. Minasov, L. Shuvalova, N. L. Inniss, O. Kiryukhina, G. Wiersum, Y. Kim, R. Jedrzejczak, N. I. Maltseva, M. Endres, L. Jaroszewski, A. Godzik, A. Joachimiak, K. J. Satchell
The paper determines the crystal structure of the SARS-CoV-2 nsp10-nsp16 heterodimer complex with S-adenosylmethionine at 1.80 Å resolution, revealing its role in viral mRNA capping and immune evasion.
bioRxiv · Apr 17, 2020 · PreprintBiochemistry