G. Minasov

This paper identifies and characterizes AdvA, a unique protein in Acinetobacter baumannii essential for cell division, revealing its structural and functional divergence from typical nucleotidyl cyclases.

The paper determines six structural states of PilU, a retraction ATPase, revealing its homohexameric assembly and conformational flexibility, which may explain its weak ATPase activity and dependence on PilT.

The paper resolves the x-ray structure of SARS-CoV and SARS-CoV-2 SUD-N/M domains and shows they have rotational flexibility, with disulfide bonds absent in pangolin-SARS and related viruses.

This paper identifies a pterin-responsive regulatory mechanism in Agrobacterium tumefaciens that controls biofilm formation through interactions between PruR, DcpA, and pterins.

This study identifies MCF, a Vibrio effector that cleaves and degrades Rab GTPases, disrupting organelle function and promoting cell death during infection.

The paper reports the x-ray structure of the MPXV protein A42R, revealing structural differences from cellular profilins that suggest distinct functional properties.

The paper determines the crystal structures of SARS-CoV-2 Nsp10/16 complexes before and after methylation, revealing the mechanism of RNA capping and its role in viral evasion of host defenses.

The paper determines the crystal structure of the ChiS DNA-binding domain in Vibrio cholerae, revealing a novel helix-sheet-helix variant of the HTH domain and its role in DNA binding.

The paper determines the structure of SARS-CoV-2 nsp16/nsp10 2'-O-methyltransferase complex with various ligands, identifying potential sites for antiviral inhibitor design.

The paper determines the crystal structure of the SARS-CoV-2 nsp10-nsp16 heterodimer complex with S-adenosylmethionine at 1.80 Å resolution, revealing its role in viral mRNA capping and immune evasion.

This study identifies Crp-regulated genes in Y. pestis during planktonic and biofilm growth, revealing its role in quorum sensing, carbon metabolism, and virulence.