Author

M. Ruiz-Ortega

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. A. Lindegaard· 1 shared C. Barbas· 1 shared C. Castillo· 1 shared C. Pyke· 1 shared D. R. Hansen· 1 shared D. Rodriguez-Puyol· 1 shared D. Serra· 1 shared H. C. Beck· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPathology

C. A. Lindegaard

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2 papers

Recent·Most cited

Ccn2 deficiency causes smooth muscle cell de-differentiation and severe atherosclerosis in hyperlipidemic mice

J. H. Larsen, J. Stubbe, H. C. Beck, M. Overgaard, C. A. Lindegaard, D. R. Hansen, R. Goldschmeding, R. R. Rodriguez-Diez, M. Ruiz-Ortega, C. Pyke, R. Wirka, J. S. Lindholt, L. M. Rasmussen, L. B. Steffensen

bioRxiv · Jan 16, 2023 · PreprintPathology

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

V. Miguel, J. Tituana, J. I. Herrero, L. Herrero, D. Serra, P. Cuevas, C. Barbas, D. Rodriguez-Puyol, L. Marquez-Exposito, M. Ruiz-Ortega, C. Castillo, X. Sheng, K. Susztak, M. Ruiz-Canela, J. Salas-Salvado, , S. Lamas

This study shows that overexpressing Cpt1a in renal tubular epithelial cells reduces fibrosis by restoring mitochondrial function and bioenergetics in CKD models and human patients.

bioRxiv · Feb 18, 2020Biochemistry