Author

J. Stubbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. A. Burnim· 1 shared A. Branstrom· 1 shared A. Gerasyuto· 1 shared C. A. Lindegaard· 1 shared C. Cui· 1 shared C. L. Drennan· 1 shared C. Pyke· 1 shared D. R. Hansen· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

A. A. Burnim

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ccn2 deficiency causes smooth muscle cell de-differentiation and severe atherosclerosis in hyperlipidemic mice

J. H. Larsen, J. Stubbe, H. C. Beck, M. Overgaard, C. A. Lindegaard, D. R. Hansen, R. Goldschmeding, R. R. Rodriguez-Diez, M. Ruiz-Ortega, C. Pyke, R. Wirka, J. S. Lindholt, L. M. Rasmussen, L. B. Steffensen

bioRxiv · Jan 16, 2023 · PreprintPathology

Ribonucleotide reductase, a novel target for gonorrhea

J. Narasimhan, S. Letinski, S. Jung, A. Gerasyuto, J. Wang, M. Arnold, G. Chen, J. Hedrick, M. Dumble, K. Ravichandran, T. Levitz, C. Cui, C. L. Drennan, J. Stubbe, G. Karp, A. Branstrom

This study identifies two novel inhibitors of Neisseria gonorrhoeae that target ribonucleotide reductase, showing efficacy against multidrug-resistant strains in a mouse model.

bioRxiv · Nov 19, 2020Microbiology

Convergent Allostery in Ribonucleotide Reductase

W. C. Thomas, F. P. Brooks, A. A. Burnim, J.-P. Bacik, J. Stubbe, J. T. Kaelber, J. Z. Chen, N. Ando

This study identifies a new allostery mechanism in Bacillus subtilis RNR through structural analysis, revealing convergent regulation of enzyme activity.

bioRxiv · Dec 21, 2018Biochemistry