Lactate potentiates differentiation and expansion of cytotoxic T cells
H. Rundqvist, P. Velica, L. Barbieri, P. Gameiro, P. Cunha, M. Gojkovic, S. Mijwel, E. Ahlstedt, I. P. Foskolou, M. Ruiz-Perez, M. Arsenian-Henriksson, J. Ule, A. Ostman, R. Johnson
This study shows that lactate enhances the anti-tumour activity of cytotoxic T cells by increasing their proliferation and cytotoxicity during exercise.
bioRxiv · Mar 9, 2019 · PreprintImmunology