4-oxo-2-nonenal Adducts In HDL Are Elevated In Familial Hypercholesterolemia: Identification Of Modified Sites And Functional Consequences
L. S. May-Zhang, V. Yermalitsky, J. T. Melchior, J. Morris, K. A. Tallman, M. S. Borja, T. Pleasent, V. Amarnath, P. G. Yancey, W. S. Davidson, M. F. Linton, S. S. Davies
This study identifies elevated 4-oxo-2-nonenal (ONE) adducts in HDL from familial hypercholesterolemia patients and shows their functional impact on HDL function and macrophage responses.
bioRxiv · May 12, 2019Biochemistry