Author

A. Pouikli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

P. Tessarz· 3 shared C. Nikopoulou· 2 shared M. Maleszewska· 2 shared S. Parekh· 2 shared Y. Hinze· 2 shared A. Annibal· 1 shared A. Antebi· 1 shared A. Mesaros· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

P. Tessarz

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Author profile →

3 papers

Recent·Most cited

Hypoxia promotes osteogenesis via regulation of the mito-nuclear communication

A. Pouikli, M. Maleszewska, S. Parekh, C. Nikopoulou, J.-J. Bonfiglio, C. Mylonas, T. Sandoval, A.-L. Schumacher, Y. Hinze, I. Matic, P. Tessarz

This study shows that high oxygen levels impair osteogenesis in MSCs by disrupting mito-nuclear communication through chromatin compaction and histone hypo-acetylation, which can be reversed by acetate supplementation.

bioRxiv · Feb 26, 2022 · PreprintCell Biology

Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle stem cell fate

K. Allmeroth, C. S. Kim, A. Annibal, A. Pouikli, C. A. Chacon-Martinez, C. Latza, A. Antebi, P. Tessarz, S. A. Wickström, M. S. Denzel

This study shows polyamines regulate hair follicle stem cell fate through translation rates and N1-acetylspermidine, which increases proliferation without reducing translation.

bioRxiv · Apr 30, 2020 · PreprintCell Biology

Deregulated mito-nuclear communication alters chromatin plasticity and differentiation potential of mesenchymal stem cells upon ageing

A. Pouikli, S. Parekh, M. Maleszewska, M. Baghdadi, I. Tripodi, C. Nikopoulou, K. Folz-Donahue, Y. Hinze, A. Mesaros, P. Giavalisco, R. Dowell, L. Partridge, P. Tessarz

This study shows that ageing reduces osteogenic potential of mesenchymal stem cells due to deregulated mito-nuclear communication, which leads to hypo-acetylation and chromatin compaction, and that acetate supplementation can reverse these effects.

bioRxiv · Apr 2, 2020 · PreprintCell Biology