Author

M. S. J. Mangan

Primary ORCID profile (0000-0001-5990-3034 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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M. S. J. ManganiD2 papers · University of Bonn

Biology Disciplines

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Heinz· 1 shared D. Jahn· 1 shared E. Latz· 1 shared F. Gorki· 1 shared F. I. Schmidt· 1 shared K. Hiller· 1 shared K. Krause· 1 shared M. Mauer· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Heinz

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJul 7, 2021

Clostridium difficile Toxin B activates the NLRP3 inflammasome in human macrophages, demonstrating a novel regulatory mechanism for the Pyrin inflammasome

M. S. J. Mangan, F. Gorki, K. Krause…·E. Latz

The paper shows that C. difficile toxin B activates the NLRP3 inflammasome in human macrophages, not the Pyrin inflammasome, and that Pyrin activation can be restored with prolonged priming.

DOI 10.1101/2021.07.07.451422

humanproteomics

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