Oral administration of a single anti-CfaE nanobody provides broadly cross-protective immunity against major pathogenic Enterotoxigenic Escherichia coli strains
A. Amcheslavsky, A. Wallace, M. Ejemel, Q. Li, C. McMahon, M. Stoppato, S. Giuntini, Z. A. Schiller, J. Pondish, J. R. Toomey, R. Schneider, J. Meisinger, R. Heukers, A. C. Kruse, E. M. Barry, , Y. Wang
This study shows that oral administration of a single nanobody provides broad protection against multiple ETEC strains by targeting conserved epitopes.
bioRxiv · Jun 16, 2020 · PreprintMicrobiology