Author

M. S. Loftus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. K. Francois· 1 shared A. L. Whitford· 1 shared A. Lewis· 1 shared A. P. Stoja· 1 shared A. R. Cliffe· 1 shared A. Rohani· 1 shared C. Boutell· 1 shared D. H. Kedes· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. K. Francois

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2 papers

Recent·Most cited

Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts

A. K. Francois, A. Rohani, M. S. Loftus, S. A. Dochnal, J. Hrit, S. McFarlane, A. L. Whitford, A. Lewis, P. A. Krakowiak, C. Boutell, S. B. Rothbart, D. Kashatus, A. R. Cliffe

This study investigates the association of HSV-1 genomes with H3K27me2 and PHF20L1 in fibroblasts, finding that H3K27me2 is linked to genome silencing and that this association is influenced by demethylase activity and transcriptional state.

mBio · Apr 10, 2024Peer-reviewedMicrobiology

Super-Resolution Microscopy Reveals Structural Mechanisms Driving the Nanoarchitecture of a Viral Chromatin Tether

M. J. Grant, M. S. Loftus, A. P. Stoja, D. H. Kedes, M. M. Smith

This study uses dSTORM to reveal the nanoarchitecture of KSHV tethers, showing they form prolate ellipsoids with LANA homodimers and exhibit polymer scaling behavior.

bioRxiv · Dec 15, 2017Microbiology